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Alkynyl Palmitic Acid肉豆蔻酸炔基

发布时间:2022-08-21   点击次数:162次

Alkynyl myristic acid is can be used to identify and characterize the post-translational myristylated proteins Alkynyl palmitic acid (15-hexadecynoic acid or Palmitic acid (15-yne)) is a modified palmitic acid with an ω-terminal alkyne. Alkynyl palmitic acid often used to identify and characterize the post-translational S-palmitoylation of proteins using the powerful click chemistry (see References).

肉豆蔻酸炔基酸可用于鉴定和表征翻译后肉豆蔻基化蛋白质。 炔基棕榈酸通常用于使用强大的点击化学识别和表征蛋白质的翻译后 S-棕榈酰化(参见参考资料)。


参考文献:

1. Gray, R. A. V., et al. (2021). Optimized Incorporation of Alkynyl Fatty Acid Analogs for the Detection of Fatty Acylated Proteins using Click Chemistry. JoVE Journal, 10 (3791), 62107. 

2. Li, B., et al. (2020). TMEM132A, a Novel Wnt Signaling Pathway Regulator Through Wntless (WLS) Interaction. Front Cell Dev Biol., 8, 599890. 

3. Lee, M.T., et al. (2020). Dietary sphinganine is selectively assimilated by members of themammaliangut microbiome. J Lipid Res 

4. White, F. K. H., et al. (2019). S-Palmitoylation of junctophilin-2 is critical for its role in tethering the sarcoplasmic reticulum to the plasma membrane. J Biol Chem., 294 (36), 13487-13501. 



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