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Emfret清除抗体Antibodies for Mouse Platelet Depletion

更新时间:2023-07-16   点击次数:369次

德国Emfret公司专注心血管和血液系统研究用抗体研发和生产,供应的抗体包括清除血液中血小板、流式细胞术鉴定分析小鼠血小板表面糖蛋白,emfret公司的抗体不仅适用于流失分析、WB检测,还可用于免疫组化/免疫荧光及免疫共沉淀检测。

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背景资料:

This antibody preparation contains a mixture of purified rat monoclonal antibodies directed against mouse GPIb (CD42b). Targeting of this receptor with divalent IgGs results in profound and irreversible Fc-independent platelet depletion in mice1,2 . Platelet depletion is frequently used to study the general role of platelets in (patho-) physiology3 .

保存条件:

The antibodies were purified from hybridoma cell culture supernatant by Protein G-Sepharose chromatography.

Stable for six months from date of shipment when stored at 4°C.

KEEP STERILE, the preparation contains no preservative. Aliquots can be stored at -20°C for at least one year. Avoid repeated freezing and thawing.

应用:

This preparation is optimized to reduce the platelet count by >95% within 60 minutes after intravenous injection of 2 µg/g bodyweight. It is recommended to inject the antibodies in a volume of 100-200 µl (diluted with sterile PBS).

同型对照(抗体来源): Rat IgG (Wistar)

缓冲液: 0.5 mg purified immunoglobulins in PBS, 0.2% (w/v) BSA, sterile filtered

浓度: 0.5 mg/ml

产品图片:

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实验结果:


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