如何研究血小板的功能?一个重要手段就是体内清除血小板,靶点科技携手德国Emfret,常备现货,推出血小板清除抗体,货号R300抗体,Antibodies for Mouse Platelet Depletion。如果4 µg抗体/g动物体重,可以持续更长时间。注射后60分钟内可以去除血小板95%以上,建议每次注射100-200µL抗体(用无菌PBS稀释)。详情联系靶点科技技术支持。
Specificity: R300抗体,Antibodies for Mouse Platelet Depletion.This antibody preparation contains a mixture of purified rat monoclonal antibodies directed against mouse GPIbα(CD42b). Targeting of this receptor with divalent IgGs results in profound and irreversible Fc-independent platelet depletion in mice. Platelet depletion is frequently used to study the general role of platelets in (patho-) physiology.
清除原理:该抗体制剂含有针对小鼠 GPIbα(CD42b) 的纯化大鼠单克隆抗体的混合物。用二价 IgG 靶向该受体导致小鼠严重且不可逆的 Fc 非依赖性血小板耗竭。血小板耗竭常用于研究血小板在(病理)生理学中的一般作用。
血小板的功能: