BroadPharm品牌的叠氮基-PEG4-NHS酯是一种非常受欢迎的PEG试剂,含有叠氮化物基团和NHS酯。亲水性PEG垫片增加了在水性介质中的溶解度。叠氮化物基团可以通过Click Chemistry与炔烃、BCN、DBCO反应,产生稳定的三唑键。NHS 酯可用于标记蛋白质、胺修饰寡核苷酸和其他含胺分子的伯胺 (-NH2)。试剂级,用于研究目的。请联系Broadpharm代理靶点科技进行GMP级查询。
Azido-PEG4-NHS ester is a very popular PEG reagent which containan azide group and an NHS ester. The hydrophilic PEG spacer increases solubility in aqueous media. The azide group can react with alkyne, BCN, DBCO via Click Chemistry to yield a stable triazole linkage. The NHS ester can be used to label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.
部分参考文献
1. Hull SM, Lindsay CD, et al 3D Bioprinting using UNIversal Orthogonal Network (UNION) Bioinks. Advanced Functional Materials. 2021. 31(7). 2007983
2. Mapes, J. H., Stover, J., Stout, H. D., Folsom, T. M., Babcock, E., Loudwig, S., ... & Swaminathan, J. (2023). Robust and scalable single-molecule protein sequencing with fluorosequencing. bioRxiv, 2023-09.
BroadPharm是一家总部位于圣地亚哥的生物技术公司,以客户为中心。公司专注于为全球客户提供高质量的PEG接头、Click Chemistry试剂、ADC接头、PROTAC接头、药物递送脂质、核苷、亚磷酰胺和标记试剂。BroadPharm成立于2009年,生产超过2000种分散的、高纯度的聚乙二醇(PEG)试剂,目前这些PEG试剂被广泛应用于生物偶联、抗体-药物偶联(ADC)治疗、药物递送以及诊断领域。具体订购,可以联系授权代理商BroadPharm代理靶点科技。