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clickchemistrytools代理现货Biotin Picolyl Azide货号1167-5选购指南

更新时间:2025-07-03   点击次数:64次

产品描述

生物素 Picolyl 叠氮 是一种先进的生物素探针,它结合了铜螯合基序,可提高反应位点 Cu(I) 的有效浓度,从而提高 CuAAC 反应的效率,从而获得更快、更具生物相容性的 CuAAC 标记。据报道,与传统叠氮化物相比,信号强度增加了 40 倍(参见精选参考文献)。


Description

Biotin Picolyl Azide is an advanced biotin probe that incorporates a copper-chelating motif to raise the effective concentration of Cu(I) at the reaction site to boosted the efficiency of the CuAAC reaction resulting in a faster and more biocompatible CuAAC labeling. Up to 40-fold increase of signal intensity, compared to conventional azides was reported (see Selected References).


产品参数

clickchemistrytools代理现货Biotin Picolyl Azide货号1167-5选购指南


化学结构

clickchemistrytools代理现货Biotin Picolyl Azide货号1167-5选购指南


精选文选


1.Wood, T. M., et al. (2021). Optimization of Metabolic Oligosaccharide Engineering with Ac4GalNAlk and Ac4GlcNAlk by an Engineered Pyrophosphorylase. ACS Chem. Biol.,

2. Banerjee, A.K.,et al. (2020). SARS-CoV-2 disrupts splicing, translation, and protein trafficking to suppress host defenses. Cells.,

3. Gaebler, A.,et al. (2016). A highly sensitive protocol for microscopy of alkyne lipids and fluorescently tagged or immunostained proteins. J. Lipid. Res., 57, 1934-47.

4. Jiang, H., et al. (2014). Monitoring Dynamic Glycosylation in Vivo Using Supersensitive Click Chemistry. Bioconjugate Chem.,, 25, 698-706.

5. Uttamapinant, C., et al. (2012). Fast, Cell-Compatible Click Chemistry with Copper-Chelating Azides for Biomolecular Labeling. Angew. Chem. Int. Ed,., 51, 5852-56.


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